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Our Science

We study healthy, rich 
and beautiful lives for all mankind.

Our Science

The company continues to develop innovative research and development, ranging from saving lives and quality of health care products.

Materials of anti-aging cosmetics

Through separate refining, synthesis, and fermentation studies,

we are developing non-polymeric and non-magnetic cosmetics materials.

Composition of anti-aging cosmetics "M4A"

BEESEN BIO has developed an anti-antification effect that is superior to EGF or EGCE from 2012 to 2016 through the international joint study of bee venom with toxicity research teams from CHA University and Strathclyde University in England.

The M4A is a material that removes Allezen from bee venom, which is more expensive than gold, and extracts only 6 % of the material(In proportion to the amount of bee venom) which is excellent for anti-aging.

It is a natural antinofluoridation component that can effectively delay and cure aging with natural products rather than artificial compounds. The effect is excellent for improving aging due to ultraviolet rays, environmental pollution, and stress.


  • ICID Registration Bee venom extract
  • PCT patent for the three countries in Korea and abroad 
  • 2 domestic / international papers 

M4A has better collagen synthesis and MMP-1 resistance compared to EGF, which is a skin regeneration material, and EGCE, which have dermatological effects.

M4A effectively controls gene expression of MMP-1 (collagen breakdown enzyme) and COL A11 (collagen synthesis) in derma

We standardized M4A raw materials through differentiated research that regulates allergic activity with a periodontal extract that is not toxic but is optimal for anti-aging activity.
 An in-vitro efficacy study found antinosis to be four times more effective than adenosine.
(Patent 10-1425018, Trademark registration 40-1030197) 


  • Result of human skin safety test at oriental bio industrial clinical support center, "Non-mastic " judgment (4 types of BEESEN cream) 
  • Results of human body application test by the Korea Institute for Skin Empathy and Research, demonstrating improvement effect of skin tone wrinkles and skin tone brushing (copper seat masks)
  • The grand prize of Apimondia

Our Science

The company continues to develop innovative research and development, 

ranging from saving lives and quality of health care products.

Materials of anti-aging cosmetics

Through separate refining, synthesis, and fermentation studies,

we are developing non-polymeric and non-magnetic cosmetics materials.

Composition of anti-aging cosmetics "M4A"

BEESEN BIO has developed an anti-antification effect that is superior to EGF or EGCE from 2012 to 2016 through the international joint study of bee venom with toxicity research teams from CHA University and Strathclyde University in England.

The M4A is a material that removes Allezen from bee venom, which is more expensive than gold, and extracts only 6 % of the material(In proportion to the amount of bee venom) which is excellent for anti-aging.

It is a natural antinofluoridation component that can effectively delay and cure aging with natural products rather than artificial compounds. The effect is excellent for improving aging due to ultraviolet rays, environmental pollution, and stress.

  • ICID Registration Bee venom extract
  • PCT patent for the three countries in Korea and abroad 
  • 2 domestic / international papers 

M4A has better collagen synthesis and MMP-1 resistance compared to EGF, which is a skin regeneration material, and EGCE, which have dermatological effects.

M4A effectively controls gene expression of MMP-1 (collagen breakdown enzyme) and COL A11 (collagen synthesis) in derma

We standardized M4A raw materials through differentiated research that regulates allergic activity with a periodontal extract that is not toxic but is optimal for anti-aging activity.
 An in-vitro efficacy study found antinosis to be four times more effective than adenosine.
(Patent 10-1425018, Trademark registration 40-1030197) 

  • Result of human skin safety test at oriental bio industrial clinical support center, "Non-mastic " judgment (4 types of BEESEN cream) 
  • Results of human body application test by the Korea Institute for Skin Empathy and Research, demonstrating improvement effect of skin tone wrinkles and skin tone brushing (copper seat masks)
  • The grand prize of Apimondia

BEESEN BIO Co.,Ltd. 

Representative : Ahn Chang-Ki 

Add : 343, Eopilgak-ro, Geumseong-myeon, Geumsan-gun, Chungcheongnam-do, Republic of Korea
Business license number : 314-81-96665   |    A mail-order number : 2015-충남금산-0001 

 CustomerCenter : 1644-0542 (Week : 09:00~ 18:00 / Lunch : 12:00~13:00 / Closed on Sat, Sun, Holiday


Copyright ⓒ 2018 BEESEN BIO. All rights reserved.

     BEESEN BIO Co.,Ltd.   |   Representative : Ahn Chang-Ki   |   Add : 343, Eopilgak-ro, Geumseong-myeon, Geumsan-gun, Chungcheongnam-do, Republic of Korea
     Business license number : 314-81-96665   |   A mail-order number : 2015-충남금산-0001  |  CustomerCenter : 1644-0542 (Week : 09:00~ 18:00 / Lunch : 12:00~13:00 / Closed on Sat, Sun, Holiday

     Copyright ⓒ 2018 BEESEN BIO. All rights reserved.