Archivement

A biotechnology revolution for healthier
and happier lives takes place.

Archivement


BEESEN BIO is growing into a global biotechnology company 

based on its accumulated R&D know-how for 10 years.

We have accumulated various research achievements by spurring R & D activities such as governmental research projects and numerous academic papers as well as acquiring industrial property rights such as domestic and foreign patent, utility model, and trademark registration.


National policy research

Research Project Title
Research period
Development of preventive and therapeutic agent for industrial animal diseases based on Korean bee venom
2011.08~
2013.08
Animal antibiotics mixed with bee venom (bee venom liquid) and medicinal plant extracts
2011.11 ~ 2014.08
Research and development of atopic dermatitis using Bee venom
2012.03 ~ 2013.02
Development of control technology for major infectious diseases of bees
2012.11 ~ 2015.10
Develop safe and effective anti-aging cosmetics containing bee venom bioactive substances
2012.11 ~ 2015.10
Developed a sustained-release melittin spray formulation to prevent pig RPPS
2013.09 ~ 2015.08
Development and industrialization of bee nemaje disease treatment
2011.08 ~ 2012.07
Development of preventive and therapeutic agent for honey bee protozoa
(Nogema, amoeba)
2012.10 ~ 2017.06
Developed adjuvant for poultry sodom virus vaccine using bee venom fraction
2016.07 ~ 2017.12

Self research

Research Project Title
Research period
Study on the effect of bee venom on diabetes and rheumatoid arthritis
2016.06 ~
Clinical trials and bee medicines registration for honeybee infestation
2011.06~
2011.11
Development and industrialization of bee nemaje disease treatment
2011.08 ~ 2012.07
Development of bee tick remedies for non-residual components (essential oils, etc.) in honey
-

Paper

Field of paper
Paper Title
Uploading address
Uploading Date
Immunology
Immunoprophylactic effects of administering honeybee (Apis melifera) venom spray against Salmonella Gallinarum in broiler chicks
J Vet Med Sci

2013.10.30
Immunology
Poly D,L-lactide-co-glycolide (PLGA) nanoparticle-encapsulated honeybee (Apis melifera) venom promotes clearance of Salmonella enterica serovar Typhimurium infection in experimentally challenged pigs through the up-regulation of T helper type 1 specific immune responses.
Vet Immunol Immunopathol
2014.10.15
Biology
An LCMS method for the assay of melittin in cosmetic formulations containing bee venom.
Anal Bioanal Chem.
2015.05.08
Toxinology
Honeybee (Apis mellifera) Venom Reinforces Viral Clearance during the Early Stage of Infection with Porcine Reproductive and Respiratory Syndrome Virus through the Up-Regulation of Th1-Specific Immune Responses.
Toxins
2015.05.22
Synthesis
Preformulation Studies of Bee Venom for the Preparation of Bee Venom-Loaded PLGA Particles.
Molecules
2015.08.18
Cosmetology
Multiple Benefits of Bee Venom in Aged Skin Manifestations.
Kor.
J.Aesthet
Cosmetol.
2015.10.30
Immunology
Effect of Bee Venom and Its Fractions on the Release of Pro-Inflammatory Cytokines in PMA-Differentiated U937 Cells Co-Stimulated with LPS.
2016.04.06
Agriculture
EVALUATION OF ANTIMICROSPORIDIAN ACTIVITY OF PLANT EXTRACTS ON NOSEMA CERANAE
J.APIC.SCI
2016.10.28
Agriculture
ANTI-NOSEMOSIS ACTIVITY OF ASTER SCABER AND ARTEMISIA DUBIA AQUEOUS EXTRACTS
J.APIC.SCI
2018.01.10

Patent

Nation
Name of invention
Registration Number
Korean
Plate for Separating Queen Bee and Its Manufacturing Method
10-0977603
Korean
BEE VENOM COMPOSITION HAVING IMPROVED GROWTH RATE AND IMMUNE FUNCTION
10-1391911
Korean
AN AUTOMATIC SUPPLYING DEVICE OF REARING LIQUID FOR BEE AND MANUFACTURING METHOD THEREOF
10-125142
Korean
THE HONEY CONCENTRATOR
10-1270995
Korean
LIPID WATER SOLUBLE BEE VENOM EXTRACTS FOR IMPROVING IMMUNITY AND FOR CURING INFLAMMATION AND FOR CURING PAIN AND COMPOSITION FOR PARENTERAL MEDICINES AND MANUFACTURING METHOD OF THE SAME
10-1418881
Korean
DEVICE FOR COLLECTING APITOXIN
10-1240291
Korean
Cosmetic composition for anti-aging comprising lipid soluble fraction of bee venom and method for manufacturing the same
10-1425018
Korean
FOUNDATION HONEY COLLECT DEVICE
10-1561504
Korean
Sustained-Release Preparations for preventing or treating porcine Salmonella typhimurium infection and PRRS Virus and Method of Preparing the Same
10-1671376
Korean
KNIFE FOR PICKING HONEY
10-1810849
Korean
Cosmetic composition comprising extracts of bee venom and method for manufacturing the same
10-1841344
Korean
Composition comprising an extract of Artemisia lvandulaefolial or Aster scaberl for treating insect disease
10-186662
PCT
PLASTIC HONEYCOMB FOR BEEKEEPING, AND METHOD FOR MANUFACTURING SAME
PCT/KR2010/009177
(출원)
PCT
ANTI-AGING COSMETIC COMPOSITION COMPRISING FAT-SOLUBLE FRACTIONS OF BEE VENOM, AND METHOD FOR PREPARING SAME
PCT/KR2013/010714
(출원)
USA
14646389(출원)
Euro
13856722.7(출원)
China
201380061546
(출원)
PCT
COSMETIC COMPOSITION INCLUDING APITOXIN EXTRACT, AND METHOD OF MANUFACTURING SAME
PCT/KR2016/004144
(출원)

Achivement


BEESEN BIO is growing into a global biotechnology company 

based on its accumulated R&D know-how for 10 years.


We have accumulated various research achievements by spurring R & D activities such as governmental research projects 

and numerous academic papers as well as acquiring industrial property rights such as domestic and foreign patent, utility model, and trademark registration.


National policy research
DivisionSupporting organizationResearch Project TitleParticipating organizationsResearch period
National policy research
Ministry of Agriculture, Food and Rural Affairs
Development of preventive and therapeutic agent for industrial animal diseases based on Korean bee venom
Chonnam National University, Chungnam National University, Proteomtech
2011.08 ~ 2013.08
Small & Medium
Business Administraion
Animal antibiotics mixed with bee venom (bee venom liquid) and medicinal plant extractsChonnam National University,
Institute of Biotechnology
2011.11 ~ 2014.08
Ministry of EducationResearch and development of atopic dermatitis using Bee venom
Daejeon National University
2012.03 ~ 2013.02
Ministry of Agriculture, Food and Rural Affairs
Development of control technology for major infectious diseases of bees
Kyonggi National University and 6 other institutions
2012.11 ~ 2015.10
Korea Institute for Advancement of TechnologyDevelop safe and effective anti-aging cosmetics containing bee venom bioactive substancesStrathclyde University, UK,
CHA University
2012.11 ~ 2015.10
Ministry of Trade, Industry and EnergyDeveloped a sustained-release melittin spray formulation to prevent pig RPPSChonnam National University,
Chungnam National University
2013.09 ~ 2015.08
Ministry of Knowledge EconomyDevelopment and industrialization of bee nemaje disease treatment
Hannam University2011.08 ~ 2012.07
Ministry of Trade, Industry and EnergyDevelopment of preventive and therapeutic agent for honey bee protozoa
(Nogema, amoeba)
Chungbuk National University
2012.10 ~ 2015.07
2015.07 ~ 2017.06
Ministry of Trade, Industry and EnergyDeveloped adjuvant for poultry sodom virus vaccine using bee venom fractionKonyang University2016.07 ~ 2017.12

Self research
Division
Supporting organization
Research Project Title
Participating organizations
Research period
Self research
-
Study on the effect of bee venom on diabetes and rheumatoid arthritis
Chungbuk National University
2016.06 ~
-
Clinical trials and bee medicines registration for honeybee infestation
Daejeon National University
2011.06~2011.11
-
Development and industrialization of bee nemaje disease treatment
Chungbuk National University
2011.08~2012.07
-
Development of bee tick remedies for non-residual components (essential oils, etc.)
 in honey
-
-

Paper
DivisionField of paperPaper TitleUploading addressUploading Date
Paper
Immunology
Immunoprophylactic effects of administering honeybee (Apis melifera) venom spray against Salmonella Gallinarum in broiler chicks
J Vet Med Sci
2013-10-30
Immunology
Poly D,L-lactide-co-glycolide (PLGA) nanoparticle-encapsulated honeybee (Apis melifera) venom promotes clearance of Salmonella enterica serovar Typhimurium infection in experimentally challenged pigs through the up-regulation of T helper type 1 specific immune responses.
Vet Immunol Immunopathol
2014-10-15
Biology
An LCMS method for the assay of melittin in cosmetic formulations containing bee venom.
Anal Bioanal Chem.
2015-05-08
Toxinology
Honeybee (Apis mellifera) Venom Reinforces Viral Clearance during the Early Stage of Infection with Porcine Reproductive and Respiratory Syndrome Virus through the Up-Regulation of Th1-Specific Immune Responses.
Toxins
2015-05-22
Synthesis
Preformulation Studies of Bee Venom for the Preparation of Bee Venom-Loaded PLGA Particles.
Molecules
2015-08-18
Cosmetology
Multiple Benefits of Bee Venom in Aged Skin Manifestations.
Kor.J.Aesthet.Cosmetol.
2015-10-30
Immunology
Effect of Bee Venom and Its Fractions on the Release of Pro-Inflammatory Cytokines in PMA-Differentiated U937 Cells Co-Stimulated with LPS.
Vaccines
2016-04-06
Agriculture
EVALUATION OF ANTIMICROSPORIDIAN ACTIVITY OF PLANT EXTRACTS ON NOSEMA CERANAE
J.APIC.SCI
2016-10-28
Agriculture
ANTI-NOSEMOSIS ACTIVITY OF ASTER SCABER AND ARTEMISIA DUBIA AQUEOUS EXTRACTS
J.APIC.SCI
2018-1-10

Patent
DivisionNationName of inventionRegistration dateRegistration number
Patent
Korea
Plate for Separating Queen Bee and Its Manufacturing Method
2010.08.17
10-0977603
Korea
BEE VENOM COMPOSITION HAVING IMPROVED GROWTH RATE AND IMMUNE FUNCTION
2014.04.28
10-1391911
Korea
AN AUTOMATIC SUPPLYING DEVICE OF REARING LIQUID FOR BEE AND MANUFACTURING METHOD THEREOF
2013.04.01
10-125142
Korea
THE HONEY CONCENTRATOR
2013.05.29
10-1270995
Korea
LIPID WATER SOLUBLE BEE VENOM EXTRACTS FOR IMPROVING IMMUNITY AND FOR CURING INFLAMMATION AND FOR CURING PAIN AND COMPOSITION FOR PARENTERAL MEDICINES AND MANUFACTURING METHOD OF THE SAME
2014.07.07
10-1418881
Korea
DEVICE FOR COLLECTING APITOXIN
2013.02.28
10-1240291
Korea
Cosmetic composition for anti-aging comprising lipid soluble fraction of bee venom and method for manufacturing the same
2014.07.24
10-1425018
Korea
FOUNDATION HONEY COLLECT DEVICE
2015.10.13
10-1561504
Korea
Sustained-Release Preparations for preventing or treating porcine Salmonella typhimurium infection and PRRS Virus and Method of Preparing the Same
2016.10.26
10-1671376
Korea
KNIFE FOR PICKING HONEY
2017.12.14
10-1810849
Korea
Cosmetic composition comprising extracts of bee venom and method for manufacturing the same
2018.03.16
10-1841344
Korea
Composition comprising an extract of Artemisia lvandulaefolial or Aster scaberl for treating insect disease
2018.06.04
 10-186662
PCTPLASTIC HONEYCOMB FOR BEEKEEPING, AND METHOD FOR MANUFACTURING SAME
2010.12.21(Application)
PCT/KR2010/009177(Application)
PCTANTI-AGING COSMETIC COMPOSITION COMPRISING FAT-SOLUBLE FRACTIONS OF BEE VENOM, AND METHOD FOR PREPARING SAME
2013.11.25(Application)
PCT/KR2013/010714(Application)
USA14646389(Application)
Europe13856722.7(Application)
China201380061546(Application)
PCTCOSMETIC COMPOSITION INCLUDING APITOXIN EXTRACT, AND METHOD OF MANUFACTURING SAME
2016.04.21(Application)
PCT/KR2016/004144(Application)

BEESEN BIO Co.,Ltd. 

Representative : Ahn Chang-Ki 

Add : 343, Eopilgak-ro, Geumseong-myeon, Geumsan-gun, Chungcheongnam-do, Republic of Korea
Business license number : 314-81-96665   |    A mail-order number : 2015-충남금산-0001 

 CustomerCenter : 1644-0542 (Week : 09:00~ 18:00 / Lunch : 12:00~13:00 / Closed on Sat, Sun, Holiday


Copyright ⓒ 2018 BEESEN BIO. All rights reserved.

     BEESEN BIO Co.,Ltd.   |   Representative : Ahn Chang-Ki   |   Add : 343, Eopilgak-ro, Geumseong-myeon, Geumsan-gun, Chungcheongnam-do, Republic of Korea
     Business license number : 314-81-96665   |   A mail-order number : 2015-충남금산-0001  |  CustomerCenter : 1644-0542 (Week : 09:00~ 18:00 / Lunch : 12:00~13:00 / Closed on Sat, Sun, Holiday

     Copyright ⓒ 2018 BEESEN BIO. All rights reserved.